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A symbiotic filamentous gut fungus ameliorates MASH via a secondary metabolite–CerS6–ceramide axis | Science

The gut microbiota is known to be associated with a variety of human metabolic diseases, including metabolic dysfunction–associated steatohepatitis (MASH). Fungi are increasingly recognized as important members of this community; however, the role of … Source link

A symbiotic filamentous gut fungus ameliorates MASH via a secondary metabolite–CerS6–ceramide axis | Science Read More »

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Intracellular protein editing enables incorporation of noncanonical residues in endogenous proteins | Science

The ability to study proteins in their native cellular context is crucial to our understanding of biology. In this work, we report a technology for intracellular protein editing, drawing from split intein–mediated protein splicing, genetic code expansion,… Source link

Intracellular protein editing enables incorporation of noncanonical residues in endogenous proteins | Science Read More »

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Deep-sea mining interests cannot shape research | Science

Although understanding deep-sea ecosystems will require decades of additional scientific work (1), activation for the first time of the socalled “2-year rule” (2) in 2021 has put pressure on the International Seabed Authority (ISA) to rush the creation and adoption of a mining code. Negotiations related to mining in international waters should not be subject

Deep-sea mining interests cannot shape research | Science Read More »

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China’s pet squirrel trade needs regulation | Science

HomeScienceVol. 388, No. 6746China’s pet squirrel trade needs regulationBack To Vol. 388, No. 6746 Full accessLetter Share on China’s pet squirrel trade needs regulationYueqin Yang, Jishan Xiang, and Xianfeng YiAuthors Info & AffiliationsScience1 May 2025Vol 388, Issue 6746pp. 480-481 PREVIOUS ARTICLEBenefits of onshoring forestry rely on sciencePreviousNEXT ARTICLEDeep-sea mining interests canno… Source link

China’s pet squirrel trade needs regulation | Science Read More »

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Emergence and interstate spread of highly pathogenic avian influenza A(H5N1) in dairy cattle in the United States | Science

Highly pathogenic avian influenza (HPAI) viruses cross species barriers and have the potential to cause pandemics. In North America, HPAI A(H5N1) viruses related to the goose/Guangdong 2.3.4.4b hemagglutinin phylogenetic clade have infected wild birds, … Source link

Emergence and interstate spread of highly pathogenic avian influenza A(H5N1) in dairy cattle in the United States | Science Read More »

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