Platelet factor 4–induced TH1-Treg polarization suppresses antitumor immunity | Science



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The tumor microenvironment (TME) contains a number of immune-suppressive cells such as T helper 1–polarized regulatory T cells (TH1-Treg cells). However, little is known about the mechanism behind the abundant presence of TH1-Treg cells in the TME. We …



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